How Does Paracetamol and Codeine work?

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Paracetamol is one of the opioid pain relievers. It is a pain-relieving and fever-lowering substance, but it has only a weak anti-inflammatory effect. The mechanism of action is not clearly understood. It has been proven that paracetamol has a significantly stronger inhibition of production of Prostaglandins (inflammation-causing messenger substances) in the brain than in the rest of the body's tissues. It may affect the perception of pain. 

Paracetamol also inhibits the effect of fever-inducing substances on the center of temperature regulation in the brain stem. It explains the fever-lowering effect.

Codeine is related to morphineOpioid from the group ofopioid pain relievers and relieves pain in the brain. Codeine can also suppress the urge to cough. The effect is dose-dependent.

Some studies indicate that the combination of substances provides more intense pain inhibition than the individual substances, even if used in higher doses.

Mode of action

These medicines contain the pain reliever paracetamol and codeine and also known as Co-codamol. 

Codeine is an ingredient in opium and one of the weak-acting opioids. It relieves pain and calms coughs. The pain-relieving effects of codeine and paracetamol complement each other, so it makes sense to use them in a fixed combination. The preparations are rated as "suitable" for moderate to severe pain if the dosage of the individual components corresponds to the individual requirements.

Method of use and dosage

Effervescent tablets of 500 mg of paracetamol and 30 mg of codeine phosphate.

In adults, taking 1-2 tablets 1-3 times a day is generally sufficient to reduce painful symptoms, even severe ones.

Instead, your doctor should review the dosage mentioned above for childhood, adolescence, senile, or kidney disease patients.

Paracetamol-containing agents can be used in impaired liver function; such a problem occurs with alcohol abuse or liver inflammation, which has a stronger effect. Then an otherwise harmless dose can already lead to symptoms of intoxication. For tips on avoiding an overdose, see Paracetamol Poisoning.

If these remedies are taken more than ten days a month for a longer period, permanent headaches can result. The risk of damage to the kidneys also increases.

Contraindications

You can find information on when you must not take these agents under Paracetamol and Codeine. Since these are combination agents, the statements made by all the respective combination partners apply simultaneously.

Side effects

You can find the unwanted effects under Paracetamol and Codeine. Since these are combination agents, the statements made by all combination partners apply at the same time.

Codeine causes respiratory paralysis, but only if you take vast amounts of it. The number of breaths decreases after just 30 milligrams of codeine. You should bear this in mind if you give a baby a pain reliever containing codeine or if, despite the warnings, you drink alcohol.

Special instructions

For children and young people under 18 years of age

In older children, because of the codeine content, the remedy is only acceptable if acute pain cannot be sufficiently relieved with pain relievers such as ibuprofen or paracetamol. Buy Co Codamol Online is not intended for children under the age of twelve.

The dosage should then be as low as possible, and you should stop the intake after three days. In addition, codeine should not be used in children between 12 and 18 years of age if their respiratory function is impaired, for example, due to respiratory disease, if they have a neuromuscular disorder, or have had surgery on the tonsils or tonsils. Such children are more prone to breathing problems.

For pregnancy and breastfeeding

During pregnancy, you should only take pain medication if necessary. Codeine can cross the placenta and thus reach the unborn child. The short-term use of paracetamol and codeine is justifiable, but only if the pain reliever ibuprofen alone does not work sufficiently or cannot be given for moderately severe symptoms. 

Tramadol is most likely to be represented as a powerful opioid. Especially in the last trimester of pregnancy, prolonged use or higher doses of codeine can cause the newborn to have breathing problems.

Ibuprofen is also the first choice as a pain reliever for mild to moderate symptoms during breastfeeding. If this alone does not work enough or cannot be used, the most likely strong pain reliever is morphine. It is best not to take codeine while breastfeeding.

To be able to drive

Drowsiness, tiredness, dizziness, and visual disturbances can impair or even make impossible the ability to actively participate in traffic, use machines, and work without a secure footing. It is expected, especially at the beginning of treatment, when the dose is increased and after a product change. People with stable treatment, on the other hand, may well be able to drive. Therefore ask the doctor to assess your ability to drive.

From this point in time, a good effect can no longer be guaranteed.If you have an expired medicinal product, it must not be disposed of with normal household waste, nor can it be disposed of via wastewater.

Conclusion

Co-Codamol must be in a place inaccessible to children! Do not take this medicine after the expiry date. You can legally buy Co-Codamol online without a prescription. It is possible to order Co-Codamol without a prescription by issuing an online prescription for which a small online questionnaire has to be filled out. Consult our experts to know more.